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Arizona knows it still has to run its offense even without its most dynamic playmaker and will be looking to a number of players to fill the void.
Fifth-year pro Kerwynn Williams gets the first chance to fill the void at running back for the Cardinals, though there will be a committee behind him.
David Johnson did it all for Arizona's offense in 2016, but coach Bruce Arians likes Kerwynn Williams and other RBs should the Cardinals need them.