Lance Moore, John Gilmore ruled out

New Orleans Saints wide receiver Lance Moore (hamstring) and tight end John Gilmore (toe) have been ruled out of Saturday's game against the San Francisco 49ers.

Neither Moore nor Gilmore practiced this week.

Linebacker Jonathan Vilma rested his sore knee Thursday but practiced Wednesday and coach Sean Payton believes he will play. Vilma does not appear on the Saints' injury report.

Safety Roman Harper tweaked his ankle this week but practiced Thursday and is hopeful of being able to play. He's probable.

Linebacker Jonathan Casillas (knee) is questionable.

John Clayton is a senior writer for ESPN.com.