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Mike Wells ESPN Staff Writer 

The Broncos are about to turn to Brock Osweiler at quarterback. Osweiler went 2-0 vs. the Colts in 2016 as Houston's starting quarterback.

Mike Wells ESPN Staff Writer 

The Colts already have two sacks and there's still 90 seconds left in the first quarter. This is just the sixth time this season that they've had at least two sacks in the game, which is why it's important that they look to acquire a pass rusher during the offseason.

Jeff Legwold ESPN Senior Writer 

Doctors are walking Trevor Siemian toward locker room -- he was holding left arm/shoulder after sack.

Nick Wagoner ESPN Staff Writer 

The shoulder injury to 49ers RT Trent Brown continues to linger as he didn't practice for a second day in a row. Brown has missed two of past three games with that injury and doesn't look to be on a good trajectory to play Sunday against Tennessee. That's not good news for the Niners as the Titans have racked up 20 sacks in the past three weeks, including two games with eight in each.

Nick Wagoner ESPN Staff Writer 

49ers Thursday practice report: Did not participate -- T Trenton Brown (shoulder), DT DeForest Buckner (not injury related), DT Earl Mitchell (not injury related). Limited participation -- TE Garrett Celek (knee), S Adrian Colbert (thumb, thigh), CB Greg Mabin (calf), WR Louis Murphy (illness), LB Mark Nzeocha (hamstring), S Eric Reid (knee, rib), CB Ahkello Witherspoon (knee). Full participation -- DE Elvis Dumervil (not injury related), TE George Kittle (ankle), T Joe Staley (not injury related).

Alden Gonzalez ESPN Staff Writer 

Rams RB Todd Gurley was asked how weird it would be to face a Seahawks team without Richard Sherman and Kam Chancellor. He smiled. "God is good," he joked.

Jeff Legwold ESPN Senior Writer 

That has been a theme of the season for Broncos as the offense turned it over and the defense, despite its rankings for much of the season, didn't hold the opponent after sudden change. Colts turned Siemian interception into 7-0 lead in seven-play drive.

Mike Wells ESPN Staff Writer 

Jacoby Brissett's 7-yard touchdown run marked just the third time this season that the Colts scored a first quarter touchdown. And it was just their 13th touchdown on 33 tries inside the red zone this season.

Jeff Legwold ESPN Senior Writer 

That was Trevor Siemian's 10th interception in a road game this season.

Alden Gonzalez ESPN Staff Writer 

Rams WR Robert Woods and OLB Connor Barwin were full participants in today's practice. LT Andrew Whitworth (knee) did not practice. RT Rob Havenstein (knee) was limited. ILB Mark Barron and C John Sullivan were limited, but not because of injury.

Alden Gonzalez ESPN Staff Writer 

The Seahawks' injury report is quite exhaustive.

Brady Henderson ESPN 

Bobby Wagner and K.J. Wright missed practice again today. That's a particularly discouraging sign for Wright, who's in the concussion protocol and is running out of time to get cleared for Sunday's game against the Rams. Mike Davis was a full participant, so it looks like he'll be available as he said yesterday that he would be.

Mike Wells ESPN Staff Writer 

Pacers (possible All-Star) guard Victor Oladipo checking out the Colts

Mike Wells ESPN Staff Writer 

Colts WR TY Hilton working on sideline catches in the end zone. Hilton only has one touchdown in the past four games

Mike Wells ESPN Staff Writer 

The Colts going with the all-blue uniforms for Thursday's game vs. Broncos