"I don't think it's positive [news],'' Chiefs coach Andy Reid said. "We'll see what the MRI shows.''
Berry was carted off with 4:56 remaining in the game. He logged seven tackles, including four solo and one for a loss, before leaving with the injury.
Berry, 28, is playing in the first season of a six-year deal that reportedly included $40 million guaranteed and a $20 million signing bonus.
Last season, Berry tied his career high with four interceptions and returned two of them for touchdowns to tie for the NFL lead in that category. He also earned the fifth Pro Bowl selection of his career.
Off the field, Berry has been a positive voice in Kansas City's locker room and an inspiration to many of his teammates. Berry was diagnosed with Hodgkin lymphoma in November 2014 but returned to play by the start of the 2015 season and was named the AP Comeback Player of the Year.