Jordan Reed, Jamison Crowder out vs. Seahawks

ASHBURN, Va. -- The Washington Redskins have ruled out four starters, including tight end Jordan Reed, and declared two others as doubtful for Sunday's game at Seattle, further depleting a team that has dealt with a number of injuries in recent weeks.

In addition to Reed, who is battling a hamstring injury, left guard Shawn Lauvao (stinger) and defensive lineman Matt Ioannidis (hand) won't play. Reserve tight end Niles Paul (concussion) also was ruled out.

On Saturday, the Redskins also downgraded wide receiver Jamison Crowder from questionable to out.

Left tackle Trent Williams (knee) and center Spencer Long (knees) are doubtful, along with backup offensive tackle Ty Nsekhe (core muscle).

Meanwhile, five players were listed as questionable, including four starters: guard Brandon Scherff (knee), running back Rob Kelley (ankle), cornerback Bashaud Breeland (groin) and safety Montae Nicholson (shoulder).

In all, three-fifths of the Redskins' starting offensive line won't play, and a fourth, Scherff, is questionable. But Scherff at least participated in practice the past two days, though in limited fashion. Coach Jay Gruden had said Thursday that "things are looking up" in regard to Scherff, and Friday did nothing to alter that outlook.

Gruden had expressed concern about Crowder's availability Thursday, and the wide receiver has said his focus remains on the long term. He was hampered by a sore hamstring early in the season but said in recent weeks that it had felt good.

"I don't want to make it worse and have it lingering for the rest of the season," Crowder said. "It's kind of tricky. It feels good at times, and then I go out and work, and it doesn't feel like bad, but it doesn't feel I can be as explosive to [where] I feel I can go out and compete at a high level."

Ryan Grant could replace Crowder in the slot. Washington also could keep Brian Quick active and use him at the Z receiver position. The Redskins have wanted to avoid using Terrelle Pryor and Josh Doctson together, with Gruden saying they have primarily worked at the X position. But losing Reed and Crowder could force them to look more for Doctson and Pryor, who had a combined four targets Sunday against the Dallas Cowboys.

Along the line, T.J. Clemmings will start at left tackle with Arie Kouandjio at right guard and rookie Chase Roullier at center. If Scherff can play, it would give the Redskins two starters on the right side, along with tackle Morgan Moses.

At tight end, rookie Jeremy Sprinkle will play in any sets using two tight ends along with veteran Vernon Davis.