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Biggest NFL injuries of Week 11

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Perine can be the workhorse for rest of season (0:42)

Mike Clay breaks down the fantasy impact Samaje Perine can make the rest of the season, where he can handle the bulk of the carries in Washington, but won't catch as many passes. (0:42)

Here are the most significant NFL injuries in Week 11:

Monday

Mike Davis, RB, Seattle Seahawks: Davis had some big moments during Monday night's contest against Atlanta, but exited during the Seahawks' opening drive of the second half. After Davis was examined on the sideline, the team declared him out for the duration of the game due to a groin injury.

Shaquill Griffin, CB, Seattle Seahawks: Griffin exited the game after being shaken up on the first defensive series of the game while making a tackle. He was replaced by the recently signed Byron Maxwell. Griffin was taken back to the locker room to be evaluated for a concussion, and declared doubtful to return.

Sunday

Jake Elliott, K, Philadelphia Eagles: The Eagles announced during the second quarter that placekicker Elliott was being evaluated for a head injury. The team subsequently indicated that Elliott would be out for the remainder of the game.

Robert Woods, WR, Los Angeles Rams: Woods was not a part of the Rams' final offensive possession, as he had suffered a shoulder injury, and had been brought to the locker room. Woods was still being checked out during Sean McVay's post-game press conference, so details were sparse at that time.

On Monday, McVay revealed that while the injury is not too serious, he will be out "a couple weeks," per ESPN's Alden Gonzalez.

Alex Okafor, DE, New Orleans Saints: Okafor was carted to the locker room after limping off the field with an unspecified leg injury that he suffered on a Washington TD pass in the fourth quarter.

On Monday, it was revealed that the Saints have lost Okafor to a season-ending Achilles tendon tear. According to ESPN's Mike Triplett, backup defensive tackle David Onyemata and backup edge rushers Hau'oli Kikaha, Trey Hendrickson and Al-Quadin Muhammad should all play greater roles going forward.

Kelvin Benjamin, WR, Buffalo Bills: Benjamin got hit in his right knee by Chargers safety Adrian Phillips, and the knee bent back awkwardly. He grabbed the knee immediately and was tended to on the field by Buffalo medical personnel before being helped off. After being examined in the medical tent on the sideline, he was carted off to the locker room and declared out for the remainder of the game.

Vincent Rey, LB, Cincinnati Bengals: Rey exited the game in the second half and was declared out for the duration of the contest because of a left hamstring injury.

Micah Hyde, S, Buffalo Bills: Injured during a rushing play by Chargers fullback Derek Watt, Hyde was designated as questionable to return because of a knee issue.

Stephon Gilmore, CB, New England Patriots: With the Pats well in control in the second half, Gilmore left the field and was deemed questionable to return because of dehydration. He returned in the fourth quarter.

Danny Amendola, WR, New England Patriots: After teammate Gilmore went back to the locker room because of dehydration, Amendola joined him, also suffering from the effects of dehydration. Similarly, he was declared questionable to return; also similarly, he made his return in the fourth quarter.

Johnny Holton, WR, Oakland Raiders: The Raiders announced during the second quarter that Holton was being evaluated for a concussion. Holton passed the tests and returned to action in the second half.

Chris Thompson, RB, Washington Redskins: Thompson appeared to take the worst of a massive collision involving Kirk Cousins and two Saints defenders and remained down on the field as his right leg was attended to by Redskins medical personnel. He was helped off the field and loaded onto the cart as teammates gathered around him. An air cast was placed on his right leg, and he was declared out for the remainder of the contest.

After the game, Redskins coach Jay Gruden indicated that Thompson has a fractured fibula and will require surgery.

D'Onta Foreman, RB, Houston Texans: At the tail end of a 34-yard touchdown run in the fourth quarter, Foreman appeared to take an awkward step, and after diving into the end zone, he remained on the ground where ankle was attended to by Texans medical staff. He was subsequently carted off the field. The early diagnosis is that Foreman has a torn Achilles tendon, pending further tests on Monday.

Marshon Lattimore, CB, New Orleans Saints: While breaking up a pass attempt in the end zone against Josh Doctson, Lattimore appeared to tweak his left leg and was attended to on the field before walking to the sideline with a noticeable limp. He was declared questionable to return, but made his return in the second half. It was a short-lived return, however, as he was involved in a hard collision on his first play back and left the game again before heading to the locker room.

Jay Cutler, QB, Miami Dolphins: At the start of the second half, the Dolphins replaced Cutler with Matt Moore and then announced that Cutler was being evaluated for a concussion. The team later announced that Cutler would not return to the game.

Leonard Floyd, LB, Chicago Bears: Floyd and Bears CB Kyle Fuller collided during a Lions running play, and Floyd was attended to on the field by Bears medical personnel for a leg injury. He was eventually carted off and was declared out for the duration of the game. Afterward, Bears coach John Fox indicated that the injury is expected to be "fairly serious."

Clay Matthews, LB, Green Bay Packers: Matthews was examined in the Packers' sideline medical tent during the break between the first and second quarter and was subsequently declared questionable to return because of a groin injury. He was later downgraded to out.

Damarious Randall, CB, Green Bay Packers: Randall landed on his head after he gave up a touchdown to Mike Wallace early in the third quarter. He received medical attention on the field before making his way up the tunnel to the Packers' locker room. Randall returned to the game later in the third quarter.

Kevin Johnson, CB, Houston Texans: Johnson left the game in the fourth quarter, and the Texans announced that he was being evaluated for a concussion.

Kayvon Webster, CB, Los Angeles Rams: Webster was declared out for the game because of a concussion.

Shawn Lauvao, OG, Washington Redskins: Lauvao exited the game in the second quarter with a stinger and was originally declared questionable to return before being downgraded to out.

Emmanuel Ogbah, DE, Cleveland Browns: Ogbah suffered a foot injury and was declared out for the remainder of the game in the third quarter. After the game, the team confirmed that Ogbah has a broken foot.

Nickell Robey-Coleman, CB, Los Angeles Rams A thigh injury sidelined Robey-Coleman in the second quarter against the Vikings, and he was declared doubtful to return.

Xavier Rhodes, CB, Minnesota Vikings: Rhodes got tangled up while defending a long pass in the second quarter and was declared questionable to return with a calf injury. Mackensie Alexander filled in for Rhodes, with Terence Newman taking over in the slot. Rhodes returned later in the second quarter.

Sammie Coates, WR, Cleveland Browns: The third-year pro exited the game against the Jaguars in the first half and was declared questionable to return because of a knee/ankle injury. He was later downgraded to out.

Montae Nicholson, S, Washington Redskins: Nicholson sustained a concussion during the game against New Orleans and was ruled out for the remainder of the contest.

Olivier Vernon, DE, New York Giants: Vernon was shaken up in the first quarter after chasing after (and diving towards) Chiefs QB Alex Smith. He was declared questionable to return with a shoulder injury.

Donald Payne, LB, Jacksonville Jaguars: Payne exited the game in the first quarter and was declared questionable to return with a hamstring injury.

Derron Smith, S, Cleveland Browns: Smith sustained a knee injury in the first quarter against the Jaguars and was designated as questionable to return.

Ross Cockrell, CB, New York Giants: Cockrell was shaken up early in the first quarter after being kneed in the head by a hurdling Travis Kelce.

Thursday

Brian Orakpo, LB, Tennessee Titans: Orakpo briefly left the game against Pittsburgh but is not expected to miss any additional action.