Jackson is nursing a hamstring injury that he sustained in San Diego's win over the Dolphins Sunday. The wideout entered that game with an abdomen injury, but exited during the second quarter with what coach Norv Turner classified as a "muscle strain," according to the report.
Jackson's status for Sunday's game against the Denver Broncos is unclear.
The team suspects the hamstring injury was triggered as a result of overcompensating for the abdomen strain, according to another report in the San Diego Union-Tribune.
The Chargers are already without All-Pro tight end Antonio Gates (foot).
Jackson leads the Chargers with 374 receiving yards and three touchdowns.