Michael Vick, Jeremy Maclin out

The Philadelphia Eagles have ruled out quarterback Michael Vick (ribs), wide receiver Jeremy Maclin (hamstring and shoulder), cornerback Dominique Rodgers-Cromartie (ankle), linebacker Moise Fokou (ankle) and tackle King Dunlap (concussion) for Thursday night's game in Seattle against the Seahawks.

Cornerback Nnamdi Asomugha (knee) and running back LeSean McCoy (toe) are questionable and will be game-time decisions. Both were limited in Wednesday's practice.

The Eagles (4-7) have to rebound quickly from a 38-20 loss to the Patriots for their game at Seattle (4-7).

Vince Young will start again at quarterback for Philadelphia, his third straight start. Young threw for a career-best 400 yards against the Patriots, though his numbers were inflated a bit because of the score.

Young -- and the Eagles -- certainly would benefit if DeSean Jackson stepped up and made some plays.

Jackson dropped three passes Sunday, including two that likely would have been touchdowns, and shied away from contact before being benched in the fourth quarter. He vowed he would bounce back against the Seahawks.

Even if Asomugha can't go, Philadelphia's defense should fare a bit better against Seattle after being carved up by Tom Brady and the Patriots. The Seahawks are 30th in the league in total offense (294.1 yards per game) and are averaging 15.2 points in their past six games.

Information from ESPN.com senior NFL writer John Clayton and The Associated Press was used in this report.