Prosecutors say a man on an Isla Vista apartment balcony made nasty comments to Misi and his friends as they walked down the street in April 2011.
Misi broke down the apartment door and struck 19-year-old Casey Scott Fisher.
As part of a plea deal, the 6-foot-3, 251-pound football player pleaded no contest Thursday to battery causing serious bodily injury.
The Santa Barbara News-Press says Misi paid Fisher for medical expenses and agreed to 400 hours of community service.
The judge is expected to reduce the count to a misdemeanor during sentencing in February.
Defense lawyer Adam Braun declined to comment.