"This loss is squarely on one man's shoulders," an aggravated Ryan said after the game. "It's on my shoulders."
One week after the Bills' defense held Indianapolis Colts quarterback Andrew Luck to a 63.6 quarterback rating, the Patriots gained 507 net offensive yards, including 466 passing yards from Tom Brady -- the most passing yards the Bills have ever allowed in a game.
"[Bill] Belichick outcoached me," Ryan said. "No question about it, and that's where the game ... that's how it ended up, and it's unfortunate. The plan has to be better on defense. Can't give up 500 yards and beat anybody, and then we turn it over three times.
"We did a horse s--- job, and it's my responsibility."
Asked what Ryan meant by getting outcoached by Belichick, Ryan responded: "Hey, man, I just know his team won. Again."
Despite the loss, Williams continued to express confidence in the Bills' locker room after the game.
"We came up short," Williams said when speaking on the Bills' response to an injury to safety Aaron Williams. "We're gonna come back, though. We're gonna play this team two more times. And it's just a learning standpoint."
Asked to elaborate on whether he meant that the Bills would meet the Patriots in the playoffs, Willimas responded, "Of course."