| Passing Leaders | |||||||||||
| PLAYER | TEAM | RESULT | COMP | ATT | YDS | TD | INT | SACK | FUM | RAT | |
Tom Brady |
1. Tom Brady, QB | NE | L 24-23 at SEA | 36 | 58 | 395 | 2 | 2 | 1 | 0 | 79.3 |
| 2. Andy Dalton, QB | CIN | L 34-24 at CLE | 31 | 46 | 381 | 3 | 3 | 2 | 1 | 87.3 | |
| 3. Ben Roethlisberger, QB | PIT | L 26-23 at TEN | 24 | 40 | 363 | 1 | 1 | 1 | 0 | 87.8 | |
| 4. Carson Palmer, QB | OAK | L 23-20 at ATL | 23 | 33 | 353 | 1 | 1 | 3 | 1 | 102.2 | |
| 5. Christian Ponder, QB | MIN | L 38-26 at WSH | 35 | 52 | 352 | 2 | 2 | 4 | 1 | 83.2 | |
| Rushing Leaders | ||||||||||
| PLAYER | TEAM | RESULT | CAR | YDS | AVG | TD | LNG | FUM | ||
Shonn Greene |
1. Shonn Greene, RB | NYJ | W 35-9 vs. IND | 32 | 161 | 5.0 | 3 | 21 | 0 | |
| 2. Robert Griffin III, QB | WSH | W 38-26 vs. MIN | 13 | 138 | 10.6 | 2 | 76 | 0 | ||
| 3. Ahmad Bradshaw, RB | NYG | W 26-3 at SF | 27 | 116 | 4.3 | 1 | 23 | 0 | ||
| 4. DeMarco Murray, RB | DAL | L 31-29 at BAL | 14 | 93 | 6.6 | 0 | 28 | 0 | ||
| 5. Felix Jones, RB | DAL | L 31-29 at BAL | 18 | 92 | 5.1 | 1 | 22 | 0 | ||
| Receiving Leaders | ||||||||||
| PLAYER | TEAM | RESULT | REC | YDS | AVG | TD | LNG | FUM | ||
Wes Welker |
1. Wes Welker, WR | NE | L 24-23 at SEA | 10 | 138 | 13.8 | 1 | 46 | 0 | |
| 2. A.J. Green, WR | CIN | L 34-24 at CLE | 7 | 135 | 19.3 | 2 | 57 | 0 | ||
| 3. Calvin Johnson, WR | DET | W 26-23 at PHI | 6 | 135 | 22.5 | 0 | 37 | 0 | ||
| 4. Percy Harvin, WR | MIN | L 38-26 at WSH | 11 | 133 | 12.1 | 0 | 23 | 0 | ||
| 5. Jeremy Maclin, WR | PHI | L 26-23 vs. DET | 6 | 130 | 21.7 | 1 | 70 | 0 | ||
| Defensive Leaders | ||||||||||
| PLAYER | TEAM | RESULT | SOLO | AST | TOT | SACK | FF | INT | TD | |
Daryl Washington |
1. Daryl Washington, LB | ARI | L 19-16 vs. BUF | 12 | 2 | 14 | 0.0 | 1 | 0 | 0 |
| 2. Ray Lewis, LB | BAL | W 31-29 vs. DAL | 8 | 6 | 14 | 0.0 | 0 | 0 | 0 | |
| 3. Bobby Wagner, LB | SEA | W 24-23 vs. NE | 7 | 7 | 14 | 0.0 | 0 | 0 | 0 | |
| 4. Jerrell Freeman, LB | IND | L 35-9 at NYJ | 7 | 7 | 14 | 0.0 | 0 | 0 | 0 | |
| 5. DeMeco Ryans, LB | PHI | L 26-23 vs. DET | 10 | 3 | 13 | 0.0 | 0 | 0 | 0 | |