General manager Scott Howson announced the moves Wednesday.
Huselius has missed the last 22 games with a lower-body injury from a game at Chicago on Oct. 23. He has three goals and two assists in seven games this season. He has 179 goals and 254 assists for 433 points in 628 career games with the Florida Panthers, Calgary Flames and Blue Jackets.
MacKenzie injured his lower body against the New York Rangers on Dec. 11 and is listed as day to day. He has two goals and three assists in 23 games with the Blue Jackets this season and has five goals and eight assists in 87 career games with the Atlanta Thrashers and Blue Jackets.