Zetterberg has missed the first two games of the Wings' opening-round series against the Phoenix Coyotes with a left knee injury. Detroit has won both games without its leading scorer, but travels to Phoenix for Game 3 having barely escaped Game 2.
"We played two good home games," Zetterberg said Sunday. "The last one got really close."
The Coyotes trailed 4-0 before scoring three unanswered. The Red Wings held on for a 4-3 win.
"They had a few power plays and a five-on-three and all of a sudden you're right back in the game," Zetterberg said. "It happens quickly in hockey and you've just got to respond and I think we did."
Zetterberg had 80 points during the regular season, 18 more than any teammate. The Swede missed the last two games of the regular season as well after getting checked by Carolina's Bryan Allen in a loss to the Hurricanes.
Information from The Associated Press contributed to this report.