After the game, Detroit coach Jeff Blashill told reporters that Howard got a skate caught on the ice and will miss at least a week.
Howard had made two saves on three shots before leaving.
The 32-year-old goaltender was playing in his 12th game this season. He had a 5-5 record and an NHL-fourth-best 1.76 goals against average entering the game.
Information from The Associated Press was used in this report.