McDavid had a pair of assists in the league's final game of the regular season and ended his campaign with 30 goals and 70 assists in 82 games.
McDavid is the second Oilers player to win the Art Ross trophy as scoring champion, joining Wayne Gretzky, who won seven times with the franchise. The second-year center becomes the first Oilers player to reach the century mark since Doug Weight in 1995-96 (104 points).
McDavid, 20, is the third-youngest scoring champion, behind Sidney Crosby (2006-07) and Gretzky (1980-81), according to ESPN's Stats & Information.
Edmonton will open the playoffs at home against the San Jose Sharks on Wednesday.