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Edinson Cavani was on target again as Paris St Germain maintained their nine-point lead at the top of Ligue 1 with a 3-1 home win against Caen.
Caen began their Coupe de la Ligue campaign with a 1-0 victory away to Ligue 2 side Lorient.
Monaco returned to winning ways after beating Caen 2-0 at Stade Louis II.
Inter Milan have signed forward Yann Karamoh from Caen, while Gabriel Barbosa has moved to Benfica on loan.
Neymar scored a brace, won a penalty and provided two assists as 10-man PSG closed out Toulouse 6-2 in the former Barcelona star's home debut.
Caen secured Ligue 1 survival in the most dramatic fashion thanks to Ronny Rodelin's injury-time equaliser away to Paris Saint-Germain.
Monaco restored their three-point lead over Paris Saint-Germain at the summit of Ligue 1 after coming from behind to defeat Dijon 2-1.
Monaco extended their lead at the top of Ligue 1 as Radamel Falcao's second-half goal secured a 1-0 win at Angers.
Monaco forward Kylian Mbappe received a standing ovation from Caen supporters after the rising star of French football scored twice in a 3-0 win.
Mario Balotelli struck his 10th league goal of the season to lead the fightback as French title contenders Nice drew at home with Caen 2-2 on Friday.
A late penalty from Edinson Cavani gave PSG a 1-0 win over Nancy on Saturday to move them level on points atop Ligue 1 with both Monaco and Nice.
Paris Saint-Germain moved into second place in Ligue 1 by thrashing Marseille 5-1, while Memphis Depay scored a brace in Lyon's rout of Metz.
Ronny Rodelin's fifth goal of the season helped Caen move out of the Ligue 1 relegation zone after a 1-0 win against Nancy on Tuesday.
Mario Balotelli was sent off for the third time this season in Ligue 1 as Nice leapfrogged Paris Saint-Germain into second place in the table.
Radamel Falcao added Monaco's other two goals as the prolific pacesetters restored their three-point advantage over Paris Saint-Germain in Ligue 1.
Lucas Moura came off the bench to score a stoppage-time winner as Paris St Germain beat Lille 2-1 at Parc des Princes.
Radamel Falcao scored two second-half goals as Monaco moved three points clear in Ligue 1 with a 3-0 victory in their top-of-the-table derby vs. Nice.
Julian Draxler scored twice as Paris Saint-Germain beat Rennes in the Coupe de France. Monaco are still alive after surviving against Chambly.
Yassine Benzia scored twice against his old club as Lille won 2-1 at Lyon, with the hosts missing the chance to close up on the Ligue 1 leaders.
Argentine striker Emiliano Sala scored for Nantes midway through the second half.
Nice exited the French Cup after a 2-1 defeat at the hands of Lorient, while Marseille's fine form continued in a 2-1 win away to Toulouse.
Julian Draxler scored in his first competitive game for Paris Saint-Germain as they routed fellow Ligue 1 side Bastia 7-0 in the Coupe de France.