Club Brugge won their second Belgian title in three years with a 1-1 draw at their closest challengers Standard Liege on Sunday.
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The Belgo-Congolese wideman has signed a new contract which should keep him at the club until 2021.
Southampton midfielder Jordy Clasie has joined Club Brugge on loan for the rest of the season.
Izquierdo, 25, has signed a four-year deal and joins for an undisclosed fee, reported to be around £13.5 million.
Brighton's record signing Jose Izquierdo has been granted a work permit by the Football Association.
Newly promoted Seagulls have agreed personal terms with the 25-year-old and a fee with the Belgian club.
The Vancouver Whitecaps announced the signing of Australia international Bernie Ibini from Belgian club Club Brugge on Monday.
U.S. international goalkeeper Ethan Horvath has become the first American to play a game for Club Brugge in their 125-year history, the club announced
U.S. national team goalkeeper Ethan Horvath has signed with Belgian champion Club Brugge, the club announced on Tuesday.
FC Copenhagen ended their Champions League Group G campaign with a 2-0 victory over Club Brugge.
Triumphant Leicester boss Claudio Ranieri insists the Foxes will produce another fairytale after reaching the Champions League knockout stages.
Leicester jumped out to a quick 2-0 lead over Club Brugge and held on for a 2-1 to clinch Group G and advance to the last 16 of the Champions League.
Leicester booked their place in the knockout stages of the Champions League after surviving a second-half rally to beat Club Brugge 2-1.
Club Brugge striker Jelle Vossen admits the Belgian side are being mocked as a Champions League laughing stock.
Porto moved up to second in Champions League Group G with a 1-0 home victory over Club Brugge.
Andre Silva's 90th-minute penalty snatched a 2-1 Champions League win for Porto at Club Brugge.
FC Copenhagen claimed a comfortable 4-0 victory over Club Brugge in Champions League Group G at Telia Parken on Tuesday night.
Leicester had wobbled before their UCL trip to Belgium, but two Riyad Mahrez goals showed the Foxes are just fine, writes Miguel Delaney.
Rampant Leicester marked their Champions League debut in stunning style as they thrashed Club Brugge 3-0.