VENUE: Jules Otten Stadion
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Club Brugge won their second Belgian title in three years with a 1-1 draw at their closest challengers Standard Liege on Sunday.
Onyekuru, on loan from Everton, is set to make his first senior appearance of 2018 as he continues his recovery.
Former Chelsea and Real Madrid man Claude Makelele steered Eupen to safety after an incredible last-day finale in Belgium's top flight.
Romelu Lukaku has expressed a desire to rejoin Anderlecht after his contract with Manchester United expires.
Arsenal have sent midfielder Jeff Reine-Adelaide and striker Chuba Akpom, plus Krystian Bielik, out on loan for the rest of the season.
U.S. international Kenny Saief has joined Anderlecht on loan from fellow Belgian club Gent.