Galatasaray missed the chance to overtake Schalke in the Champions League Group D standings as they were held to a 0-0 draw by the German side on Wednesday.
It proved a frustrating night for the Turkish league leaders who struggled to create chances from their greater share of possession while Schalke were the more dangerous side.
Galatasaray's best chance in the first half saw striker Eren Derdiyok blast a close-range effort straight at Schalke goalkeeper Alexander Nubel.
Schalke were the better side after the break, forcing home keeper Fernando Muslera into several fine saves.
Breel Embolo did have the ball in the net for Schalke but his effort was ruled offside.
The draw left Schalke in second place with five points and Galatasaray in third on four. Porto lead with seven.
"We didn't get the result we wanted, but even one point on a stage like the Champions League is huge," Galatasaray defender Ozan Kabak said. "We would have liked a win on our home turf."