Leicester City's Nampalys Mendy fired home the decisive spot kick as they beat Southampton 6-5 on penalties after a 0-0 draw on Tuesday to book a Carabao Cup quarterfinal clash with holders Manchester City.
Southampton had a Steven Davis goal disallowed by the video assistant referee late in the second half and hit the crossbar through Manolo Gabbiadini in stoppage time with the match going straight to penalties without extra time.
After 10 successive penalties found the net, Gabbiadini's weak effort was saved by Leicester keeper Danny Ward and Mendy slotted home the winner.
The fourth-round fixture was originally scheduled for last month but was postponed after the Leicester chairman Vichai Srivaddhanaprabha was killed in a helicopter crash.
Southampton's 18-year-old striker Michael Obafemi had the game's first real chance when he toe-poked wide after 22 minutes, but it was his miss in the second half that is likely to play on his mind for a little longer.
Nathan Redmond's effort came down off the crossbar and dropped at Obafemi's feet, but he somehow contrived to prod wide.
Southampton thought they had taken the lead with eight minutes remaining after Redmond bundled his way into the box before Davis swept home.
His effort, however, was chalked off by the VAR for a handball against Redmond after the ball had cannoned into the Southampton winger's arm as he battled into the area.
Gabbiadini hit the bar with a dipping, curling free kick in stoppage time before Southampton's luck deserted them further in the shootout.
Leicester will be at home to City in the last eight, while Arsenal host Tottenham, Burton Albion travel to Middlesbrough and Chelsea and Bournemouth play at Stamford Bridge in the quarterfinal ties set to be played on Dec. 18 and 19.