Pacquiao was getting hammered by Juan Manuel Marquez's left jabs in their clashes. Now he's facing the left-handed firepower of a man three weight divisions bigger than JMM. Oscar TKO 10.
It isn't just size but also a style matchup for Pacquiao. De La Hoya is all wrong for Pacquiao. Unless the Golden Boy has declined seriously, which is possible, I'll go with Oscar by TKO.
A lot of folks think this is a De La Hoya blowout because of his size advantage. I don't buy that. I think it will be a competitive fight, but I also think Oscar will get the job done via a midround TKO.