Federer, injuries headline Australian Open

Everything begins and ends in the same thought: Roger Federer.

He is such a dominant No. 1 right now, similar to the days when women like Martina Navratilova, Chris Evert, Steffi Graf or Monica Seles dominated. Every time Federer plays it's like he's a three-touchdown favorite.

We haven't seen the likes of this on the men's side in a long, long time. Pete Sampras was an incredible No. 1, but he would still lose every so often in the small tournaments. Federer is on a tremendous run (winning six of the last 10 Grand Slam events), and he's pacing himself tremendously well by not overplaying. He's really peaking for each of the majors. So he obviously goes into the Australian Open as the huge favorite to win.

Now, with all of the injuries, there's a cloud of uncertainty for the rest of the men's field. It's a crushing blow to the men's side that Andre Agassi and Rafael Nadal are out of the tournament, because I expected both to be able to challenge Federer. Nadal brings such excitement and personality to the court -- plus, he's my favorite player to watch. Defending champion Marat Safin, who beat Federer in the semifinals last year, withdrew Tuesday because of tendinitis in his right knee. Federer doesn't need any help to begin with, and with Agassi and Nadal out, it really lessens the men's field.

The absence of Agassi and Nadal is a huge benefit for Andy Roddick, because he will now be the No. 2 seed and on the opposite side of the bracket from Federer. His game is well-suited for Australia and we could be looking at a Roddick-Federer final.

Roddick has the monster weapon (his serve) and when the courts are hot, his game plays quite a bit faster. (Federer always says he likes the court slower.) When the surface is faster, it makes
Roddick's serve that much harder to break. The fans wanted to see Roddick and Federer become a rivalry, but considering Federer has won 10 of 11 matches against Roddick, it's pretty lopsided.

If Roddick can win in a big match over Federer, it will turn his career around. That's what he needs more than anything to jump-start his career. And if he can get one against Federer at a Grand Slam, that will take his game to another level. Of the four majors, the best chance Roddick has against Federer is in Australia. (If Roddick is the No. 2 seed, the only time he can play Federer is in finals.)

Like Agassi, Roddick really prospers in 100-degree weather. He relishes it and for a lot of these players early in the year, coming from Europe, the hot weather doesn't agree with them as much. That could be another big advantage for Roddick.

Lleyton Hewitt will be scrappy and will probably be around as the tournament goes on. Tomas Berdych is one to watch and David Nalbandian can play well Down Under. The two young Frenchmen, Richard Gasquet and Gael Monfils, could make some noise and perhaps Andrew Murray as well. All of these young guys are worth watching, but I'll be shocked if, on the final weekend, you don't see Federer for the title.

Brad Gilbert, former top-5 player and former coach of Andre Agassi, is providing ESPN.com with analysis throughout the Australian Open. For more, log onto bradgilberttennis.com