Zvonareva won the Prague Open earlier this month after losing to Serena Williams in the final at Charleston in her previous tournament. In between, Zvonareva posted a three-set win over Vania King on clay to clinch victory for Russia in the Fed Cup semifinals against the United States.
Zvonareva improved to 32-7 overall this year.
Also Monday, 11th-seeded Agnes Szavay routed Yan Zi 6-1, 6-1 to advance on an overcast day at the Foro Italico. Virginie Razzano easily defeated Julia Vakulenko 6-1, 6-2, while Virginia Ruano Pascual eliminated Anastasia Rodionova 6-1, 6-3.
Samantha Stosur marked her return to the WTA Tour with a 6-3, 6-2 victory over 42nd-ranked Michaella Krajicek. Stosur, a former doubles No. 1, had been out for several months because of illness. She will next face seventh-seeded Venus Williams.
Two-time Rome champion Amelie Mauresmo is missing the tournament with a rib injury. Top-ranked Justine Henin also pulled out, citing fatigue, and Dinara Safina withdrew with a back injury Monday, one day after winning the German Open.