Federer, who beat Bedene 6-3 6-4 6-3, faced questions from actor Will Ferrell in the immediate aftermath of his victory on court.
"Roger, tonight you seemed like a gazelle out there on the court," Ferrell said. "Would you describe your game as a silky gazelle?
"Maybe, maybe not," Federer replied. "Don't they get eaten at the end?"
"You're 36 years old, you seem ageless," Ferrell continued. "Are you a witch or a vampire?"
After a brief moment, Ferrell was asked himself which one was better to which he replied: "Probably a vampire."
Federer faces world No.176 Jan-Lennard Struff in the second round of the tournament.