Ferrer, ranked No. 4, is a heavy favorite to win his second tournament of the season. He won in Auckland, New Zealand, last month.
The first-round match was postponed Tuesday because of rain in the Argentine capital.
In another first-round match postponed from Tuesday, David Nalbandian defeated fellow Argentine Carlos Berlocq 6-3, 2-6, 6-3. Also, sixth-seeded Fabio Fognini defeated Guillermo Garcia-Lopez 7-5, 6-3.