Watkins said in a statement:
"I am very thankful for the past three years at Clemson University that have enabled me to grow academically, athletically, and spiritually. After much prayerful consideration, I have decided to take the next step in pursuing my lifelong dream of playing in the NFL.
"I would not have this opportunity without the support and encouragement of my family, coaches, teammates, and the best fans in college football. No matter where my next steps may lead, I will always take pride in the PAW and will forever be a part of the Clemson family."
Watkins leaves Clemson with 23 school records, including single-season and career marks for receptions and the single-season mark for receiving yards.