Unless an injury befalls one of them, Sunday's game against the Jacksonville Jaguars will be the 158th start together for Manning and Saturday.
"The chemistry between those two is a must for a quarterback to be successful," Kelly said. "I was blessed because I had Kent Hull for more than 90 percent of the snaps that I took in the NFL."
Although the quarterback gets the credit for audibles at the line of scrimmage, something Manning is famous for, the center plays a crucial role.
"We would go up to the line and Kent would turn to me and say 'Get out of it,' " Kelley said. "He knew based on the alignment of the nose tackle whether it was a 3-4 or a 4-3. He always knew if the play was going to work by their initial alignment when we'd get up there. I wouldn't even ask any questions or wait to look."
In the AFC East, New England Patriots quarterback Tom Brady and center Dan Koppen are on the verge of breaking into the top five. They've started 103 games together and should surpass Phil Simms and Bart Oates on Halloween. Brady and Koppen have been to four Super Bowls together and won the first three.