Can the Bills rattle QB Kevin Kolb?

Arizona Cardinals quarterback Kevin Kolb was treated like a human piñata in last week's loss to the St. Louis Rams. Kolb was sacked a season-high nine times in the Cardinals' 17-3 loss to St. Louis.

Can the Buffalo Bills do similar damage?

The Bills' defense has been shaky this year. But the Bills are playing against one of the worst offensive lines in the NFL. On paper, Buffalo's much-hyped defensive line should be able to take advantage.

Buffalo's pass rush hasn't lived up to expectations. Star defensive end Mario Williams, who signed a $100 million contract this offseason, has been particularly disappointing -- just 1.5 sacks in five games.

If there was ever an ideal matchup for Williams and Buffalo's defensive line to wake up, this is it. Arizona's pass protection is awful and Kolb is not a dominant quarterback. Rattling Kolb is Buffalo’s best chance to pull the upset this weekend and get back to .500.