Mitchell and Keisel are listed as probable for the 8:30 p.m. ET game at Heinz Field in the Steelers’ final injury report of the week.
Starting inside linebacker Ryan Shazier is listed questionable after missing the past three games because of a sprained right knee.
Safety Shamarko Thomas will miss his second consecutive game because of a hamstring injury. Starting nose tackle Steve McLendon (shoulder) and cornerback Ike Taylor (forearm) were declared out at the beginning of the week.
Texans outside linebacker Jadeveon Clowney is listed as questionable. The No. 1 overall pick of the 2014 NFL draft has missed the past five games after having early season knee surgery.
Texans coach Bill O’Brien has said Clowney will be a game-time decision.