Big 12 Week 4 game picks: League play begins with tough test for TCU

Conference play begins in parts of the Big 12 this weekend. Texas, coming off a heartbreaking, 45-44 loss to Cal, hosts Oklahoma State. In Lubbock, two undefeated teams meet. No. 3 TCU, with a patchwork defense, will open its conference schedule on the road facing Texas Tech and electrifying quarterback Patrick Mahomes.

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Here are the picks:

Maryland at West Virginia
Sept. 26, 3 p.m. ET

Oklahoma State at Texas
Sept. 26, 3:30 p.m. ET (ESPN)

No. 3 TCU at Texas Tech
Sept. 26, 4:45 p.m. ET

Unanimous picks:

Rutgers over Kansas

Baylor over Rice