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Big 12 Week 4 game picks: League play begins with tough test for TCU

Conference play begins in parts of the Big 12 this weekend. Texas, coming off a heartbreaking, 45-44 loss to Cal, hosts Oklahoma State. In Lubbock, two undefeated teams meet. No. 3 TCU, with a patchwork defense, will open its conference schedule on the road facing Texas Tech and electrifying quarterback Patrick Mahomes.

Also, visit our college football PickCenter page for additional information on these games and many more.

Here are the picks:

Maryland at West Virginia
Sept. 26, 3 p.m. ET


Oklahoma State at Texas
Sept. 26, 3:30 p.m. ET (ESPN)


No. 3 TCU at Texas Tech
Sept. 26, 4:45 p.m. ET


Unanimous picks:

Rutgers over Kansas

Baylor over Rice