A review of four hot issues from the Buffalo Bills' 27-20 loss to the New York Jets:

Pinpointing Mario's departure: Defensive end Mario Williams looks to be among the several Bills injured in this game. His final play came on the Jets' extra point following their 69-yard touchdown catch with 9:23 left in the fourth quarter. The Buffalo News reported that Williams was "limping mightily" after getting X-rays after the game. The Bills did not announce any injury to Williams, and a team spokesperson deferred comment to coach Doug Marrone, who will speak to reporters Monday afternoon.

Spiller says Jets stacked box: Running back C.J. Spiller, who ran for 9 yards on 10 carries before taking himself out of the game with a thigh injury, said the Jets were trying to force him to the edges of the field. "They wanted me to bounce it," he said. "They put a lot of people in the box and dared our passing game to beat them." Spiller, who acknowledged after a 41-yard performance in Week 1 that teams are game planning against him, echoed those thoughts again Monday. "If I'm a defensive coordinator, that would be my biggest thing, too, is to stop our run and pretty much make our rookie quarterback beat us," he said.

Wood on "unacceptable" performance: Other than Spiller's struggles that highlighted a bleak offensive day for the Bills, center Eric Wood was penalized twice for holding (one was declined). On Monday, Wood said some of Buffalo's mistakes "were terrible, [mine] included." Wood and the rest of the Bills' offensive line allowed EJ Manuel to get sacked eight times, part of an ugly 19-of-42 performance by the rookie. "We've got to complete more balls and we have to get better protection," Wood added. "Yesterday was unacceptable."

Marathon of a game: At 3 hours, 33 minutes, this was the longest Bills game in at least their past three seasons. Much of that, of course, is due to the Jets' 20 penalties, as well as their two challenges, and two booth reviews. Meanwhile, the Bills tied a team record with eight first downs off Jets penalties. They last "achieved" that feat in 1987.