"I talked to Stevie today," head coach Doug Marrone said. "He told me he thinks he'll be ready to go and be out there tomorrow, limited."
"I'll be ready for Sunday," Johnson later said.
Jackson also sat out last Wednesday's practice as he continues to "manage" a knee injury that has limited him this season.
"I'll take a look [at him] tomorrow," Marrone said. "I'm not ready to stand on a table one way or the other."
It was Spiller's first practice action in more than a week.
"Fred was down. I felt like I needed to go. I didn't want to leave Tashard Choice and [Ronnie] Wingo out there. I'm a team player," Spiller said, tongue in cheek. "There's definitely no reading between the lines, though, saying, 'Oh, he's back [at practice],' because I'm definitely not back to normal yet."
Linebacker Manny Lawson returned to practice Wednesday after missing Sunday's game in New Orleans with a hamstring injury.
Rookie wide receiver Marquise Goodwin was close to full participation, Marrone said. He wore a sleeve over his injured left elbow at the start of Wednesday's practice.
DID NOT PARTICIPATE
QB Thad Lewis (ribs)
RB Fred Jackson (knee)
DT Kyle Williams (Achilles)
WR Stevie Johnson (hip)
QB EJ Manuel (knee)
RB C.J. Spiller (ankle)
WR Marquise Goodwin (elbow)
LB Manny Lawson (hamstring)
OL Kraig Urbik (knee)