1 p.m. ET | CBS
Matchup rating: 39.7 | Spread: PIT -10.5 (46)
What to watch for: Jaguars rookie quarterback Jake Luton is making his third start and facing the league's best pass rush. The Steelers lead the NFL with 36 sacks (and are tied for second with 11 interceptions), led by T.J. Watt and Bud Dupree. If the Jaguars are going to be able to stay close and potentially pull the upset, it's going to fall heavily on offensive tackles Cam Robinson and Jawaan Taylor keeping Watt and Dupree off Luton and giving him enough time to get the ball out. -- Mike DiRocco
Bold prediction: The Steelers will hold rookie running back James Robinson to 50 yards or fewer. Robinson has earned high praise from the Steelers' coaches and players leading into this matchup -- and with good reason. He's averaging 109 yards per game in the past three games, but the Steelers look to be back at nearly full strength in the run defense with the return of Tyson Alualu (knee) a week ago and Mike Hilton (shoulder) trending toward playing this week. Without the pair, the Steelers' run defense was woeful against the Cowboys and Ravens, but it'll be motivated to prove it is an elite unit when healthy. -- Brooke Pryor
Stat to know: When the 9-0 Steelers and 1-8 Jaguars meet Sunday, it'll match the sixth-largest differential in win percentage in Week 10 or later in the Super Bowl era (excluding strike-shortened seasons). The Jaguars have allowed at least 24 points in eight consecutive games this season, their longest streak of allowing 24-plus points in franchise history. On the other side, the Steelers have scored 24-plus in all nine of their games this season, tied with the Saints for most in the NFL.
What to know for fantasy: Robinson has just 3 yards on seven targets over the past two weeks, after posting more than 7 yards per target earlier this season. A return to versatility is almost essential this weekend against the NFL's best defense in terms of running back fantasy points allowed. See Week 11 rankings.
Betting nugget: Pittsburgh is 1-10 ATS as a double-digit road favorite under coach Mike Tomlin, with four outright losses. Read more.
Pryor's pick: Steelers 35, Jaguars 17
DiRocco's pick: Steelers 31, Jaguars 14
FPI prediction: PIT, 85.8% (by an average of 14.3 points)
Matchup must-reads: Steelers get what they needed going into potential trap game vs. Jaguars ... Jaguars headed for dubious distinction under owner Shad Khan ... Tomlin says Steelers "are not a Big Ten team playing a MAC opponent" in Jaguars ... Jaguars show growth in nearly pulling off upset at Green Bay ... Jaguars place rookie CB Henderson on IR