"We definitely have that kind of relationship," Harbaugh said. "Alex and I have had this conversation before about the going up and slapping each other on the rear end and hugging before the game. Both our point of views was, 'Nah, we wouldn't do that.' That conversation came up and we were both, 'We're not into that.'"
Harbaugh said that wouldn't necessarily be because of any hard feelings between the two. Smith was the quarterback for Harbaugh and the 49ers before being benched during the 2012 season in favor of Colin Kaepernick.
Smith was then traded to the Chiefs at the end of that season.
"I've always seen him as a great quarterback, a great football player," Harbaugh said. "He plays all games like he really wants to win the game. It's a joy to coach a guy like that. He always gave you his best. He's a top-notch guy, a man I truly respect."
Kaepernick indicated he would attempt to say hello to Smith.
"We'll get a short talk in before the game, but we both know we're here for business," he said.
He also had little, but all good things to say about Smith.
"I had a great relationship with him," Kaepernick said. "He really helped me develop as a player. I attribute a lot of my success and development and coming along so quickly because of what he did for me.
"He's one of classiest people I've been around with the way he handled that situation and the way he continued to help me after I started playing. He [did] everything you could imagine to try to help this team win."