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Rapid Reaction: Brewers 6, Dodgers 3

MILWAUKEE -- Joc Pederson hit two solo home runs, but the Milwaukee Brewers hit a pair of two-run shots in the first inning and knocked off the Los Angeles Dodgers Wednesday night, 6-3, at Miller Park.

How it happened: In his first big league start this season, right-hander Joe Wieland was roughed up in the first inning, giving up two-run home runs to second baseman Scooter Gennett and first baseman Adam Lind.

In all, the Brewers put five on the board in the first. Wieland settled down after that but gave way to the Dodgers’ bullpen with two out in the fifth, having been charged with six runs on six hits and four walks while striking out a pair.

The Dodgers got a run in the fourth and then made it a 5-2 game in the fifth on center fielder Pederson’s eighth home run of the season. But Los Angeles couldn’t cash in against Milwaukee right-hander Wily Peralta, who went eight innings and scattered seven hits while striking out six. Pederson added another home run in the eighth, marking his first career multi-homer game.

Replay winner: Dodgers manager Don Mattingly has had his issues with baseball’s replay this spring, but his team caught a big break from a review Wednesday.

Wieland gave way to right-hander Sergio Santos with two on and two out in the fifth. Santos walked left fielder Khris Davis to load the bases and then walked shortstop Jean Segura to make it a 6-2 game. That brought up catcher Martin Maldonado, who smacked Santos’ first offering to third baseman Justin Turner. But Turner was slow and wide with his throw to first. Gonzalez snared the throw, but fell off the bag and first-base umpire Andy Fletcher ruled Maldonado safe. Mattingly challenged the play and it was overturned, ending the inning with no further damage.

The Dodgers are 2-for-6 on challenges this season.

Gonzalez strikes again: First baseman Adrian Gonzalez had two hits Wednesday. In three games against the Brewers, Gonzalez is 4-for-6 with five walks, three runs scored, a double, a home run and was hit by a pitch. In 27 career games at Miller Park, Gonzalez is 43-for-103 (.417) with 11 doubles, 10 home runs and 27 RBIs.

Up next: The Dodgers will try for a split of this four-game series in Milwaukee Thursday afternoon with right-hander Carlos Frias (2-0, 0.00 ERA) taking on Brewers right-hander Mike Fiers (1-3, 4.74 ERA).