1 p.m. ET | Fox
Matchup rating: 70.7 | Spread: NO -5 (51)
What to watch for: Taysom Hill will reportedly make his debut as a starting quarterback in the NFL with Drew Brees sidelined by broken ribs and a punctured lung. The Saints' choice of Hill is certainly surprising, considering fellow backup Jameis Winston played most of the second half last week and has far more experience. But the Saints and coach Sean Payton have never made it any secret about their belief that Hill could be a successful NFL quarterback despite the fact that he is a run-first player who has attempted only 20 career passes, including the playoffs. That makes this one of the NFL's most fascinating matchups of the week, as New Orleans tries to keep its six-game win streak alive against its biggest rival. -- Mike Triplett
Bold prediction: Hill will not just throw his first career NFL touchdown on Sunday -- he'll throw multiple TD passes. Hill, who has been used mainly in run situations, has attempted only 18 passes in his NFL career. But Payton will call plays to show that Hill can be effective with his arm, too. -- Mike Wells
Stat to know: The Falcons are 3-1 under interim coach Raheem Morris after an 0-5 start under Dan Quinn. They have the third-best offensive efficiency (78.8) in the NFL since Week 6, trailing only the Chiefs (89.8) and Buccaneers (79.0). In those first five weeks, they were 21st (59.2).
What to know for fantasy: Atlanta QB Matt Ryan will look to establish some fantasy consistency with a healthy roster. This season, Ryan has as many finishes as a top-eight quarterback as he does weeks outside the top 20 (three apiece). See Week 11 rankings.
Betting nugget: Atlanta is 7-1 against the spread (ATS) in its past eight road games. Read more.
Wells' pick: Saints 28, Falcons 25
Triplett's pick: Saints 26, Falcons 20
FPI prediction: NO, 73.5% (by an average of 8.4 points)