Officials flagged the San Francisco 49ers for 112 accepted and declined penalties last season.
The total is 110 this season with four games remaining.
That works out to an additional 2.2 penalties per game, the NFL's third-largest increase from last season, according to ESPN Stats & Information.
Only Detroit (+3.3) and Oakland (+2.3) have suffered larger per-game increases. Green Bay (-3.0), Baltimore (-2.3) and Cincinnati (-2.3) have made the largest per-game reductions.
The overall average has remained at 7.2 accepted and declined penalties per team.
The 49ers' totals have spiked in part because rookie right tackle Anthony Davis ranks among the NFL leaders with 11 penalties this season. Left tackle Joe Staley, now on injured reserve, went from zero penalties in nine games last season to seven in nine games this season.
Manny Lawson, playing for a new contract and perhaps trying to maximize sack totals, has gone from zero penalties last season to five this season -- four for offside or neutral-zone infractions.