What it means: The Bills (9-7) end their season on a high note, winning at New England for the first time since 2000. It's also the Bills' third win against the Patriots in their last 28 meetings and the first time the Patriots have lost at home to an AFC opponent in 36 games. The Patriots, having already locked up the AFC's top seed, sat tight end Rob Gronkowski and other key starters, and they replaced Tom Brady with rookie Jimmy Garoppolo in the second half. Either way, the Bills took care of business to finish with their first winning record since 2004.
Stock watch: Doug Marrone -- up. While this was a halfhearted effort from the Patriots, it shouldn't take away from what has been an encouraging body of work from Marrone's team this season. While the Bills didn't make the playoffs, they close out the season with a 4-2 record against divisional opponents and put themselves in position to compete next season. At this point, it's hard to justify firing Marrone.
Game ball: Bills defensive line. It's tough to pick one player from this unit, which sent three players to the Pro Bowl -- Mario Williams, Kyle Williams and Marcell Dareus -- and had one more (Jerry Hughes) with a strong case to make it. We'll have to see how Sunday's games shake out, but the Bills should finish the weekend atop the NFL's sack chart. The success of the Bills defense, and the team as a whole, starts up front.
Urbik, Glenn injured: Bills starting left guard Kraig Urbik left with a lower back injury in the second quarter and did not return. He was replaced by rookie Cyril Richardson, a fifth-round pick. Early in the fourth quarter, starting left tackle Cordy Glenn left with a knee injury and did not return. He was replaced by Chris Hairston.
What's next: The Bills' season is over. They will return to Buffalo on Sunday night and clean out their lockers Monday morning. The biggest story over the coming days will be what front-office moves, if any, owner Terry Pegula decides to make.