8:20 p.m. ET | NBC
Matchup rating: 73.4 | Spread: SEA -3.5 (44.5)
What to watch for: Will the Seahawks continue to let Russell Wilson cook? They strayed from their usual establish-the-run M.O. and dropped back to pass on 11 of their 14 first-quarter offensive plays against Atlanta. Offensive coordinator Brian Schottenheimer has said matchups will factor into how much the Seahawks throw early, and the matchup this week includes the league's reigning NFL Defensive Player of the Year in cornerback Stephon Gilmore. -- Brady Henderson
Bold prediction: Undrafted rookie running back J.J. Taylor will make a play that leads the national television audience to take notice. At 5-foot-8 and 185 pounds, he can play "hide and seek," according to running backs coach Ivan Fears, who also has compared him to Dion Lewis and Darren Sproles in terms of his physical stature. -- Mike Reiss
Stat to know: Cam Newton and Wilson have combined for five seasons with at least 3,500 passing yards and 500 rushing yards. Every other player in NFL history has combined for four such seasons.
Betting nugget: This ends the Patriots' streak of being favored in 64 consecutive games. Read more.
Reiss' pick: Seahawks 20, Patriots 17
Henderson's pick: Seahawks 27, Patriots 20
FPI prediction: SEA, 61.8% (by an average of 4.3 points)
Matchup must-reads: Belichick calls Seattle Seahawks QB Wilson underrated ... Bring your own energy: Carroll's Seahawks prepared for no fans at CenturyLink ... Did Patriots revamp their playbook for Newton? Not so fast ... Adams fires back at Jets' Gregg Williams; not 'bored' in Seahawks debut