The Patriots retweeted a photo of Andruzzi, who played on New England's three Super Bowl championship teams, carrying a woman near the scene of the explosions.
Andruzzi's charitable foundation, which had participants in the marathon, was hosting an event at a local establishment on Boylston Street, which was close to the second explosion. Andruzzi and his wife Jen were near the finish line at the time of the first explosion, greeting runners.
Andruzzi later released a statement through a public relations agency that works with his foundation.
"Marathon Monday should be about uplifting stories, personal challenges and fundraising milestones, but today's bombings irrevocably changed that," the statement said. "While I appreciate the interest in hearing our perspective on today's horrific events, the spotlight should remain firmly on the countless individuals -- first responders, medics, EMTs, runners who crossed the finish line and kept on running straight to give blood, and the countless civilians who did whatever they could to save lives. They were the true heroes. Our thoughts and prayers go out to all those affected by this senseless tragedy."
Earlier, Andruzzi had tweeted: "Jen and I are safe. … Our thoughts & prayers are with all the victims and their families impacted at today's Boston Marathon. TY to all our emergency personnel."
Andruzzi played for the Patriots from 2000-04. His three brothers were New York City firefighters involved in the Sept. 11 terrorist attacks.
In the first game after the attacks, Andruzzi carried two American flags on to the field during pregame introductions as his brothers, wearing firefighter gear, raised their helmets to the crowd.