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Randy Caballero's ankle injury shelves bout with Oscar Negrete

A right ankle injury has knocked junior featherweight Randy Caballero out of his upcoming fight with Oscar Negrete, which was due to headline "Golden Boy Boxing on ESPN" on June 30.

Caballero has been hampered by ankle pain for the past week and on Tuesday he notified Golden Boy Promotions that his doctor recommended he not fight, Golden Boy president Eric Gomez told ESPN on Wednesday.

Caballero, a former bantamweight world titleholder, was out of action for all of 2015 mainly because of a painful cyst he had to have removed from the same ankle.

"He injured the same ankle that he had surgery on, the one he had all the problems with before," Gomez said. "He's had a lot of pain and the doctor recommended that he doesn't fight. He is going back for an MRI and an X-ray to see exactly what is going on. He's been in pain since last week but we won't know if it's related to surgery until he gets the scans back. But we're going to be cautious and make sure this is not a recurrence. We want to make sure that Randy is 100 percent before he gets back in the ring."

With Caballero out, the new main event for the card (10 p.m. ET, ESPN2 and ESPN Deportes), which will take place at the Fantasy Springs Resort Casino in Indio, California, the home area of Coachella, California's Caballero, will match Negrete (16-0, 6 KOs) against Jesus Ruiz (35-8-5, 24 KOs) in a 10-round bantamweight bout. The card will be the 50th that Golden Boy will promote at the resort.

On the debut edition of "Golden Boy Boxing on ESPN" the 26-year-old Caballero (24-0, 14 KOs) won a competitive, unanimous 10-round decision against Ruiz (36-8-5, 25 KOs), 27, of Mexico, on March 23, also at Fantasy Springs.

"I am a little sad that the fight against Caballero fell through because that was the fight that I really wanted, but I am excited that I still get to fight," said Negrete, 29, a Colombia native fighting out of Rosemead, California. "Ruiz is a fierce warrior in the ring. I've seen him in the ring against notable opponents like Leo Santa Cruz, Diego De La Hoya, and most recently Caballero. He is an opponent that gives all he has, and we will both be ready to put on a great and exciting show."

Caballero was disappointed to have to withdraw from the fight.

"I want to apologize to my opponent, Oscar Negrete, and to all my fans who really wanted to watch this fight," Caballero said. "With all that has happened in my career, I didn't want to risk an ankle injury hurting my entire career. I am sure that once my ankle heals and with the support of all my fans, I will be back at 100 percent."