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Thursday night NFL best bets: Tampa Bay Buccaneers at Philadelphia Eagles

The Eagles have been tough on opposing QBs, but will they be able to slow down Tom Brady? Julio Aguilar/Getty Images

Week 6 of the NFL season kicks off Thursday with the defending champion Buccaneers visiting the Eagles.

Tampa Bay (4-1) is coming off a 45-17 thrashing of the Dolphins, while Philadelphia (2-3) is coming off a three-point win at Carolina.

ESPN betting analysts Joe Fortenbaugh (22-8-1, 4-1 last week), Doug Kezirian (9-9-2, 2-1), Tyler Fulghum (6-9, 1-3) and Anita Marks (101-59, 19-11), sports betting deputy editor David Bearman (12-8-1, 1-3), Stats & Information's Seth Walder 23-24 (5-2), Football Outsiders' Aaron Schatz (18-11, 2-5) and fantasy/betting analyst Eric Moody (20-11, 13-6) have teamed up to offer their best bets.

Odds courtesy of Caesars Sportsbook (as of Wednesday).

Tampa Bay Buccaneers (-7, 52.5) at Philadelphia Eagles

Kezirian: I backed Miami last week, but part of the loss can be attributed to Jacoby Brissett's injury. The Dolphins attacked Tampa the proper way, and I believe Philly will do the same, especially because the Eagles have run the ball the fourth-fewest times in the league. The Bucs are decimated with injuries to their secondary and needed to sign a free agent like Richard Sherman. Tampa's offense is pretty loaded, and while I lean to Philly and the points, I would rather just bet the Eagles can score.

Pick: Eagles team total over 22.5 (-105)