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College football betting: Trends point to Ohio State

The Ohio State Buckeyes enter their Week 1 matchup against the Notre Dame Fighting Irish as 17.5 point favorites. AP Photo/Jay LaPrete

Week 1 of the 2022 College Football season kicks off on Thursday night featuring plenty of marquee games that will be played over the Labor Day weekend.

Pittsburgh and West Virginia will start the holiday weekend in a battle of former USC signal callers, JT Daniels and the man who replaced him in 2019, Kedon Slovis. Saturday has a full slate of games between top-25 teams, highlighted by the defending champion No. 3 Georgia Bulldogs facing the No. 11 Oregon Ducks in the Chic-Fil-A Kickoff Game at Mercedes-Benz Stadium and the No. 5 Notre Dame Fighting Irish going up against the No. 2 Ohio State Buckeyes.

Here are all the betting nuggets, stats and information you need to know ahead a jam-packed Week 1.


Thursday

Central Michigan at No. 12 Oklahoma State
7 p.m. ET, Boone Pickens Stadium, Stillwater

Line: Oklahoma State (-21)
Money line: Oklahoma State (-1600), Central Michigan (+900)
Total: 60 points

  • Central Michigan covered five straight games, tied for the longest active streak in the FBS.

  • Oklahoma State is 15-5 ATS in last 20 non-conference games.

  • Central Michigan is 4-1 ATS in last five season openers.

  • Oklahoma State is 0-2 ATS in prior two series meetings against CMU, the under also hit in both meetings.

West Virginia at No. 17 Pittsburgh
7 p.m. ET on ESPN, Acrisure Stadium, Pittsburgh

Line: Pittsburgh (-7.5)
Money line: Pittsburgh (-305), West Virginia (+240)
Total: 52 points

  • The team favored in this matchup is 0-5 ATS and 1-4 SU in the last five meetings.

  • Pittsburgh lost each of the last four meetings SU when favored.

  • West Virginia is 3-7 ATS on the road over the last two seasons.

  • The under has hit in four of the last five meetings.


Friday

Western Michigan at No. 15 Michigan State
7 p.m. ET on ESPN, Spartan Stadium, East Lansing

Line: Michigan State (-22)
Money line: Michigan State (-2000), Western Michigan (+1050)
Total: 54 points

  • Western Michigan is 7-3 ATS in last 10 season openers.

  • Western Michigan is 7-2-1 ATS in last 10 against ranked opponents.

  • Michigan State is 1-9 ATS in last 10 as a favorite of 20 points or more.

  • Michigan State is 4-1 ATS in last five against non-conference opponents.


Saturday

Colorado State at No. 8 Michigan
12 p.m. ET on ABC, Michigan Stadium, Ann Arbor

Line: Michigan (-30.5)
Money line: Michigan (-15000), Colorado State (+2200)
Total: 61.5 points

  • Colorado State is 5-0 ATS in last five against ranked opponents.

  • Michigan is 2-6 ATS against teams from the Mountain West Conference.

  • Michigan is 1-4 ATS in last five as a favorite of 30-or-more.

  • Colorado State has not covered in last six games, tied for the fourth-longest active streak in FBS.

No. 13 NC State at East Carolina
12 p.m. ET on ESPN, Dowdy-Ficklen Stadium, Greenville

Line: NC State (-11.5)
Money line: NC State (-430), East Carolina (+328)
Total: 55 points

  • NC State 4-11 ATS in last 15 road games.

  • East Carolina is 8-2 ATS in last 10 games as a double-digit underdog.

  • East Carolina 3-1 ATS and SU in last four meetings at home against NC State.

  • NC State 5-5 ATS and SU in last 10 games as an AP Top 15 team.

No. 11 Oregon Ducks at No. 3 Georgia Bulldogs
7 p.m. ET on ABC, Mercedes-Benz Stadium, Atlanta

Line: Georgia (-17)
Money line: Georgia (-900), Oregon (+600)
Total: 53 points

  • Oregon is 1-4 ATS in last 5 AP Ranked matchups.

  • Georgia is 7-3 ATS in last 10 against ranked non-conference opponents.

  • Oregon is 1-4 ATS in last 5 as an underdog of 14 or more.

  • The under is 15-5 in Georgia's 20 against ranked opponents.

UTEP at No. 9 Oklahoma
3:30 p.m. ET, Memorial Stadium, Norman

Line: Oklahoma (-31.5)
Total: 57 points

  • UTEP is 2-8 ATS in last 10 games against AP Top 10 teams.

  • Oklahoma is 13-7 ATS in last 20 as a favorite.

  • Oklahoma failed to cover in last 3 season openers, tied for the team's longest streak over the last 40 years.

  • The over is 10-5 in Oklahoma's last 15 with a total of 57 or fewer.

No. 23 Cincinnati at No. 19 Arkansas
3:30 p.m. ET on ESPN, Razorback Stadium, Fayetteville

Line: Cincinnati (-6)
Money line: Arkansas (-240), Cincinnati (+196)
Total: 52 points

  • Cincinnati is 4-1 ATS in last five as an underdog.

  • Arkansas is 8-2 ATS in last 10 games in September.

  • Cincinnati is 8-2 ATS in last 10 against ranked opponents.

  • Arkansas is 7-3 ATS in last 10 as a ranked team.

No. 24 Houston at UTSA
3:30 p.m. ET, Alamodome, San Antonio

Line: Houston (-4)
Money line: Houston (-190), UTSA (+158)
Total: 61.5 points

  • UTSA is 4-1 ATS in last five against ranked opponents .

  • Houston is 7-13 ATS in last 20 as a road favorite.

  • UTSA is 15-5 ATS in last 20 as an underdog.

  • Houston is 3-7 ATS (6-4 SU) in last 10 as a ranked team.

Troy at No. 21 Ole Miss
4 p.m. ET on SEC Network, Vaught-Hemingway Stadium, Oxford

Line: Ole Miss (-21.5)
Money line: Ole Miss (-2000), Troy (+1050)
Total: 58 points

  • Troy is 1-4 ATS in last five as an underdog.

  • Ole Miss is 6-3-1 ATS in last 10 as double-digit favorite.

  • Troy is 1-4 ATS in last five on the road.

  • The under is 4-1in Ole Miss last five games with a total below 60.

No. 25 BYU Cougars at South Florida Bulls
4 p.m. ET on ESPNU, Raymond James Stadium, Tampa

Line: BYU (-12)
Money line: BYU (-430), South Florida (+328)
Total: 58 points

  • BYU is 1-4 ATS in last five as a road favorite.

  • South Florida is 5-0 ATS in last five as home underdog.

  • South Florida is 4-1 ATS in last five as a double-digit underdog.

  • South Florida is 5-0 ATS in last five against ranked opponents.

Rice Owls at No. 14 USC Trojans
6 p.m. ET, Los Angeles Memorial Coliseum, Los Angeles

Line: USC (-32.5)
Total: 61.5 points

  • Rice is 1-4 ATS in last five season openers.

  • USC is 1-4 ATS (2-3 SU) in last five as a home favorite.

  • Rice is 4-1 ATS in last five on the road against AP Top 15 teams.

  • USC is 4-11 ATS in last 15 non-conference games.

No. 7 Utah Utes at Florida Gators
7 p.m. ET on ESPN, Ben Hill Griffin Stadium, Gainesville

Line: Utah (-3)
Money line: Utah (-145), Florida (+122)
Total: 51 points

  • Utah 4-1 ATS in last five when favored by three or less.

  • Florida is 1-4 ATS in last five season openers against AP Ranked opponents.

  • Utah is 1-9 ATS (5-5 SU) in last 10 games in the month of September.

  • Florida is 4-1 ATS as a home underdog since 2017.

Miami (OH) at No. 12 Kentucky
7 p.m. ET on ESPN+/SECN, Kroger Field, Lexington

Line: Kentucky (-16)
Money line: Kentucky (-700), Miami (OH) (+500)
Total: 52.5 points

  • Miami is 13-7 ATS in last 20 as an underdog.

  • Kentucky is 10-4-1 ATS in last 15 as a home favorite.

  • Miami is 1-4 ATS in last five on the road.

  • Kentucky is 5-10 ATS in last 15 as a favorite of 14-or-more points.

Utah State Aggies at No. 1 Alabama Crimson Tide
7 p.m. ET, Bryant-Denny Stadium, Tuscaloosa

Line: Alabama (-41.5)
Total: 62.5 points

  • Utah State is 4-1 ATS in last five road games.

  • Alabama is 8-2 ATS in last 10 season openers.

  • Utah State is 1-4 ATS in last 5 vs AP Top 5 (lone cover was vs Alabama in 2005).

  • Alabama is 9-2 ATS at home over the last two seasons.

  • Alabama is 12-8 ATS as AP No. 1 team over last five seasons.

No. 5 Notre Dame Fighting Irish at No. 2 Ohio State Buckeyes
7:30 p.m. ET on ABC, Ohio Stadium, Columbus

Line: Ohio State (-17.5)
Money line: Ohio State (-800), Notre Dame (+550)
Total: 58.5 points

  • Notre Dame is 7-1 ATS (6-2 SU) in season openers as an underdog, over the last 45 years.

  • Ohio State is 15-4-1 ATS in last 20 season openers.

  • Notre Dame is 8-2 ATS in last 10 road games.

  • Ohio State is 7-3 ATS in last 10 regular season games against AP Top-10 opponents.

  • Notre Dame is 7-13 ATS in last 20 against AP Top-5 teams.


Sunday

Florida State at LSU
7:30 p.m. ET on ABC, Caesars Superdome, New Orleans

Line: LSU (-3)
Money line: LSU (-155), Florida State (+130)
Total: 51.5 points

  • LSU is 7-3 ATS in last 10 games on a neutral site.

  • Florida State is 4-10-1 in last 15 games in September.

  • LSU 1-4 ATS in last 5 against non-conference opponents.

  • Florida State is 4-1 ATS in last 5 against SEC opponents.


Monday

Clemson Tigers at Georgia Tech Yellow Jackets
7 p.m. ET on ESPN, Mercedes-Benz Stadium, Atlanta

Line: Clemson (-22.0)
Money line: Clemson (-2000), Georgia Tech (+1050)
Total: 49 points

  • Clemson is 7-2-1 ATS in last 10 against Georgia Tech.

  • Georgia Tech is 2-8 ATS in last 10 against AP Top-5 teams.

  • Clemson is 3-7 ATS in last 10 when favored by 21-or-more.

  • Georgia Tech is 3-7 ATS in last 10 as an underdog of 21-or-more.