Moncur missed most of last season with a torn abdominal muscle and was given a sixth year of eligibility from the NCAA for 2009. He had been working out in recent days with hopes of playing against the Seminoles on Monday night.
Miami coach Randy Shannon, though, said Wednesday that Moncur would be out for the opener. The Hurricanes also will be without defensive end Adewale Ojomo, who could miss the entire 2009 season with a broken jaw.
Shannon said there are no other major injury issues that could affect Miami for the opener and that he remains confident in his defensive line.
"Everybody else is healthy, fully healthy," Shannon said. "They've been healthy for a week. When you look at injuries, we may have an ankle here or maybe I rested a guy. Like sometimes in practice I've rested [defensive tackles] Allen Bailey and Josh Holmes and Joe Joseph some days on different days. ... We're pretty healthy right now."
When asked if he thought his team would be all right without Moncur and Ojomo, Shannon said: "We'll miss them, their experience and things like that, but we have confidence in [defensive ends] Olivier Vernon, Marcus Robinson, Andrew Smith and Steven Wesley, who has done a great job for us. We have a lot of guys who played a lot of football last year on this team at that position."
Miami's defensive line will be tested early against the Seminoles, as FSU is expected to field one of the best offensive lines in the conference this year, if not the best, and stopping the run will be one of the Hurricanes' biggest challenges Monday. Last year, in Florida State's 41-39 victory, Antone Smith rushed for a career-best four touchdowns, quarterback Christian Ponder ran for 144 yards, and the Seminoles racked up 310 rushing yards to Miami's 51.
"You've got to be able to stop the run," Shannon said. "That's what it comes down to. If you can stop the run defensively, you can make it a typical game that you want to be addressing, when you can let your pass rush get after the quarterback, and get them in long-yardage situations. Last year we weren't able to do that at certain times in the game, and Florida State did a nice job of running the football with Ponder and mixing it up with their tailbacks."
However, when the school issued its first official injury report later Wednesday, the Hurricanes said defensive end Gavin Hardin and linebacker Shayon Green were expected to miss the season because of operations. Hardin's injury was not specified, and Green's was listed as a "lower extremity."
Information from ESPN.com ACC blogger Heather Dinich and The Associated Press was used in this report.