WACO, Texas -- Nick Florence threw for 367 yards and three touchdowns, running back Lache Seastrunk had 194 total yards and Baylor won its first Big 12 game of the season, beating Kansas 41-14 Saturday.
Baylor (4-4, 1-4) led 20-14 at halftime before pulling away in the second half to snap a four-game losing streak.
Florence was 26 of 42 and surpassed 3,000 yards passing for the season. The senior had touchdown passes of 11, 68 and 40 yards.
James Sims had 126 rushing yards for Kansas (1-8, 0-6), which lost its eighth in a row and 18th straight Big 12 game. The Jayhawks last won a conference game on Nov. 6, 2010, against Colorado, now of the Pac-12.
Baylor's defense allowed 210 points during the losing streak before tightening up in the second half on Saturday.
After Ahmad Dixon intercepted a pass at the Kansas 40, Florence had a 7-yard TD run to extend Baylor's lead to 34-14 with 2:24 remaining in the third quarter.
The senior quarterback added a 40-yard touchdown pass to Tevin Reese in the fourth quarter as the Bears finished with 666 total yards.
Florence came into the game leading the nation in passing yards. He now has 3,019 yards and 25 touchdowns.
Florence hit 5 of 6 passes on the opening drive of the game.
Seastrunk, a transfer from Oregon who sat out last season, broke free in the Kansas secondary and caught a 68-yard touchdown pass to push Baylor's lead to 14-0 in the first quarter, the Bears' 11th play of 50 or more yards this season. Seastrunk had 103 yards rushing and 91 receiving.
Sims' 58-yard touchdown run cut the deficit to 14-7. The junior has rushed for more than 100 yards in five straight games.
Kansas quarterback Michael Cummings, who made his third career start just 60 miles away from his hometown of Killeen, added a 22-yard TD run in the second quarter.
Aaron Jones kicked two field goals in the second quarter, including a 22-yarder that put the Bears up 20-14 just before halftime.
The game was delayed for 46 minutes just before the start of the third quarter after lightning was reported within 7 miles of Floyd Casey Stadium.
Fans were advised to take cover for an incoming storm, but it barely rained during the stoppage. There was a light rain at the start of the third quarter that let up after several minutes.