EUGENE, Ore. -- Trailing Michigan State 27-18 in the third quarter and facing a third-and-10, Oregon quarterback Marcus Mariota found himself confronting a decision while on the run: Either pitch the ball to freshman Royce Freeman, or try a keeper.
Mariota, who is as adept with his feet as he is with his arm, decided on the flip to Freeman for the first down, and the No. 3 Ducks would go on to score the first of four unanswered touchdowns for a 46-27 victory Saturday night over the No. 7 Spartans.
Afterward, many of the Ducks -- and even the Spartans -- pointed to that play as the pivotal moment of the game, which was billed as the premier nonconference matchup of the season.
"I was looking for him to run it," said a surprised Freeman, who had a pair of rushing touchdowns in the victory. "I was going to block for him."
Mariota finished with 318 yards passing and three touchdowns, solidifying his position as an early Heisman favorite. He now has 69 touchdown passes for his career, an Oregon record.
Redshirt freshman Devon Allen had three catches for 110 yards and two touchdowns for the Ducks.
The loss snapped an 11-game winning streak for the defending Big Ten- and Rose Bowl-champion Spartans, who went 13-1 last season. Connor Cook threw for 343 yards, two touchdowns and two interceptions.
"I just tried to keep a calm mindset. I tried not to get caught up in the game, caught up in the moment at all," Cook said. "They just made more plays than us. We had some opportunities on offense and I needed to grasp them and I didn't."
The Spartans had the second-ranked defense in the nation last year, allowing opponents an average of just over 252 yards per game. But the high-flying Oregon offense -- combined with temperatures approaching 100 degrees -- appeared to wear on Michigan State as the game went on.
The two teams both went three-and-out on their opening series and it appeared that defenses would rule the day. The Spartans reached Oregon territory midway through the quarter, but on third-and-10 on the 38, Erick Dargan intercepted Cook and ran it back 36 yards.
The Ducks capped the drive when Thomas Tyner barreled over the goal line for a 1-yard touchdown, and Oregon added the conversion for an 8-0 lead.
Mariota hit Allen with a 70-yard touchdown pass to give the Ducks an 18-7 lead with 10:12 to go in the half. Allen, the NCAA's reigning 110-meter hurdles champion, shook off strong safety RJ Williamson before sprinting in for the score.
The scoring pushed Mariota past Darron Thomas (66) on Oregon's all-time list. Mariota has thrown at least one touchdown in each of the 28 games he's played at Oregon.
Michael Geiger kicked a 34-yard field goal and Cook added a 7-yard touchdown pass to Tony Lippett with 2:26 left before the break to pull the Spartans within a point. Michigan State took a 24-18 lead with 18 seconds to go when Josiah Price leaped to grab Cook's 7-yard TD pass into the end zone.
The Ducks were hurt early in the first half when junior offensive lineman Andre Yruretagoyena was carted off the field with what appeared to be a right leg injury.
Michigan State padded its lead with Geiger's 42-year-old field goal, but Mariota found Allen with another touchdown pass, this time from 24 yards out, to cut the Spartans' lead to 27-25.
It was earlier on that series that Mariota made the momentum-changing pitch to Freeman for 17 yards.
"Once I saw Royce five, 10 yards down the field, I just thought he could get there faster than I could," Mariota said.
Even Michigan State coach Mark Dantonio pointed to the play as the moment the game shifted.
"We had to stop the momentum and we had him dead to right and he got out. We had him. I even said, 'He's sacked.'" Dantonio said. "But again, you have to credit him, that's why he's the player he is."
On the next series, Oregon regained the lead on Mariota's 37-yard scoring pass to Keanon Lowe before Freeman's 38-yard TD run.
With the Spartans threatening on Oregon's 31 midway through the fourth quarter, Ifo Ekpre-Olomu intercepted a pass intended for receiver AJ Troup. Freeman added a 14-yard touchdown run for the final margin.
The Spartans' 11-game winning streak included a 34-24 victory over Ohio State in the Big Ten championship and a 24-20 victory over Stanford in the Rose Bowl.
The Ducks were the highest-ranked nonconference opponent the Spartans had faced since they played top-ranked Nebraska in 1996.
Potential Texas, Oklahoma move to SEC - The hurdles, domino effects and what we know so far
Texas and Oklahoma expressing interest in joining the SEC shook the foundation of the Big 12 and caught many high-ranking college athletics officials off guard. Can a move really happen? What would it mean for other conferences? We break down the latest.
Ryan Day wants NIL money to be spread around
Ohio State's football coach explains how down the road, he'd like to see NIL money be spread among all players in a program instead of the high-profile positions.
Pac-12 commissioner George Kliavkoff says conference not looking to add schools, but would be 'foolish' not to listen
In the wake of conference realignment rumors swirling around the SEC and Big 12, Pac-12 commissioner George Kliavkoff says his conference is not looking to add new members but would be "foolish" not to listen to any interested schools.
Ohio State Buckeyes coach Ryan Day says NIL money should be spread out among college football players
Ohio State coach Ryan Day said Friday that there should be consideration to sharing NIL money among players who won't get the same opportunities as high-profile players.
How the Big 12 is reacting to Texas' and Oklahoma's attempted SEC move
Heather Dinich provides an updated timetable on plans for Texas and Oklahoma to move to the SEC.
Source: Oklahoma Sooners, Texas Longhorns on the verge of making SEC move
Texas and Oklahoma could make their move to the SEC official in a matter of weeks, ESPN has confirmed.