STARKVILLE, Miss. -- Mississippi State coach Dan Mullen grinned broadly as he walked off the field and pumped his fist with one arm while holding his daughter, Breelyn, in the other. The deafening roar of the crowd's trademark cowbells showered the field, and the players danced in celebration.
The biggest home game in Mississippi State history had just turned into its biggest victory.
Prescott, who jumped into the Heisman Trophy conversation the past weekend with a breakout game against Texas A&M, turned in another solid performance. He completed 18 of 34 passes for 246 yards while running for 121 yards.
He also had lots of help. Josh Robinson ran for 97 yards and two touchdowns. De'Runnya Wilson caught four passes for 72 yards, including a 34-yard touchdown catch, and the Bulldogs defense bailed out the offense with red zone stops after turnovers.
"Every time we needed to make a play, a guy stepped up and made a play," Mullen said. "We always wondered how to take the next step in this league ... that's it."
Mississippi State (6-0, 3-0 Southeastern Conference) has won nine straight games going back to the past season. Auburn (5-1, 2-1), the defending SEC champion, lost for the first time since the past season's national championship game.
The Bulldogs jumped to a stunning 21-0 lead in the first nine minutes -- helped by two turnovers on Auburn's first two offensive plays -- but the Tigers pulled within 28-20 in the third quarter. They couldn't complete the comeback, though, and were undone by Ricardo Louis' fumble in the fourth quarter, untimely penalties and an inconsistent offense.
Auburn's Nick Marshall threw for 209 yards, two touchdowns and two interceptions while also running for 100 yards.
Mississippi State won despite committing four turnovers. Auburn also had four turnovers.
"We have to learn from this," Auburn coach Gus Malzahn said. "We had a similar setback to this last year. There are a lot of champions in that locker room. They are disappointed, and they should be."
The Bulldogs will find out Sunday if the victory was enough to jump Florida State and earn the first No. 1 national ranking in school history. Florida State defeated Syracuse 38-20 on Saturday.
It was Prescott's first game since a breakout performance against Texas A&M. For the most part, the 6-foot-2, 230-pound junior handled the increased scrutiny well and made plays with both his arm and feet.
Auburn couldn't overcome an awful start.
The Tigers' first offensive play was a Marshall pass that was tipped at the line of scrimmage and intercepted by Jay Hughes. The second was a fumble by receiver D'haquille Williams that was recovered by Benardrick McKinney. Mississippi State turned them both into touchdowns.
A few minutes later, Prescott rumbled into the end zone for a 2-yard touchdown and the Bulldogs -- who were hosting their first game between top five teams in school history -- had a three-touchdown advantage.
But then it was Mississippi State's turn to start committing turnovers, with four before halftime. The Bulldogs threw three interceptions -- including one by Logan Cooke on an ill-fated fake punt -- and Jamoral Graham fumbled on a punt return.
Mississippi State's defense did the job, despite Auburn's good field position. The Bulldogs held Auburn to two field goals before Marshall completed a 9-yard pass to Williams to pull the Tigers within 21-13. That quieted the cowbells for a few minutes, but they roared again late in the second quarter when Prescott ran for a 15-yard touchdown and a 28-13 lead.
Mississippi State defensive lineman Preston Smith said the school-record crowd of 62,945 played a big factor.
"There was one point where I couldn't even hear myself think," Smith said. "But that's OK. I know if I can't hear myself think, they can't either. And they're the ones calling the plays."
Auburn pulled within 28-20 on an impressive 10-play, 99-yard touchdown drive midway through the third quarter that was capped by Marshall's 15-yard throw to Williams for the score. Williams caught six passes for 108 yards and two touchdowns.
The game started in the heat and sunshine, but it was raining by halftime. Marshall's passes started sailing high in the second half, and he completed just 17-of-35 in the game.
Mississippi State went ahead 31-20 on a 21-yard field goal with 11:33 remaining. On the ensuing kickoff, Louis fumbled, and the Bulldogs recovered. Two plays later, Robinson ran for a 1-yard touchdown, and the celebration began in Starkville.
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