Conklin, an All-America candidate, has started 31 of the past 32 games at tackle for No. 2 Michigan State. He suffered the injury in last week's victory against Central Michigan and watched the end of that game from the sideline with a brace on his left knee.
Coach Mark Dantonio didn't share any details about the injury during the week other than to say that it wasn't season-ending.
Without Conklin, Michigan State will be missing both of its original starting tackles. Right tackle Kodi Kieler hasn't played since the Spartans' win over Oregon on Sept. 12 because of a right leg injury. Sophomore Dennis Finley is expected to play in Conklin's place, and fifth-year senior Donovan Clark has taken over Kieler's spot.