New Memphis coach Ryan Silverfield announced the hire Thursday and called MacIntyre "the perfect fit to lead our defense." The move is pending completion of state hiring protocols.
MacIntyre went 30-44 as Colorado's head coach from 2013 to 2018, including a 10-4 season in 2016 that included a Pac-12 South Division title. Before coaching at Colorado, MacIntyre went 16-21 at San Jose State from 2010 to 2012 and posted a 10-2 record his final year.
Ole Miss improved to 59th place of all Football Bowl Subdivision teams in points allowed per game (26.5), 85th in yards allowed per game (416.8), and tied for 83rd in yards allowed per play (5.82) with MacIntyre coordinating the defense in 2019.
Without MacIntyre last year, the Rebels ranked 113th in points allowed per game (36.2), 121st in yards allowed per game (483.4) and tied for 113th in yards allowed per play (6.32).
The MacIntyre hire comes one day after Memphis quarterback Brady White tweeted that he was returning to the Tigers for his final year of eligibility. White helped Memphis go 12-2 and win the American Athletic Conference before losing to Penn State in the Cotton Bowl.