It's so noticeable, the Heisman Trophy candidate has been dubbed "Jameis Squintston."
Cameras caught Winston regularly straining to see the play call from coaches on the sideline during the Seminoles' win against Miami. He wears contacts off the field but said Wednesday that it's uncomfortable to wear them when playing.
Winston, who is near-sighted, laughed about the whole thing and said it was just a coincidence that he went in for a refill the same week his vision became a national story.
"I squint a lot. It looks like I'm squinting now. I just do that. It's a habit," Winston said Wednesday while not wearing his contacts during his weekly news conference. "I asked them earlier today when I was in the training room, 'Pick something out. I'll let you know that I can see. Just pick anything out in the back of the room.'
"Even y'all can do it. Pick something out in the back that y'all want me to read and I will read it for you."
There were plenty of chuckles, but no one took Winston up on the offer as Florida State (No. 2 BCS; No. 3 AP) gets ready to play Wake Forest on Saturday.
Still, one expert believes Winston could be even better if he wore contacts during games.
Steven A. Hitzeman, a clinical associate professor at Indiana's School of Optometry, said there is a direct correlation between vision and athletic performance.
"Visual acuity is a strong predictor of performance," Hitzeman said. "Visual performance and athletic performance. The better you see, the better you perform.
"The better the acuity, the quicker you respond to visual stimuli. The quicker you respond to visual stimuli, the better decisions you're going to make. The quicker decisions you're going to make, the better you're going to play."
Cameras showed several instances of Winston squinting to see the sideline when coaches were signaling plays to the quarterback during the 41-14 win against Miami. He would then turn and run the offense, seemingly, without issue.
Coach Jimbo Fisher said the lights at the stadium played a factor in the squinting, but he isn't concerned at all.
"He has contacts and doesn't like wearing them, but it's a very minimal prescription," Fisher said. "At night, he has a hard time, sometimes, with the lights and where those lights are. He sees. He's fine. That's the way he looks over there.
"It's never a factor. It's never been a problem, just because he squints. He still seems to see. Think of the way he would play if he could see."
Winston is averaging 312.8 yards passing per game and has thrown 24 touchdowns and six interceptions with a 70.3 completion percentage. His 201.12 quarterback efficiency ranks No. 2 in the Football Bowl Subdivision. Only six others have a better completion percentage.
"If I was his optometrist, if I was his coach, if I was his parent, I would make sure he's wearing correction when he plays," Hitzeman said. "His performance should be better with contacts than without. ... I would think that he would see much better and play much better wearing visual correction.
"And if he wears them in baseball, there's no reason he shouldn't wear them in football."